Spoilered the sections that have been repeatedly quoted, as people have likely already read them.
Well, it looks like I'll have a bit of work ahead of me. I'll need to update
the full chronology I'd made a while back to remove all the Jeph Loeb TV series from it.
Kevin Feige Says Previous MCU TV Shows Aren’t Part Of CanonWhile at CCXP Brazil, he spoke with Brazilian pop culture site Omelete about the Marvel projects and when asked about how the visual language of the Disney+ series will compare to the MCU, he first responded by stating that “Disney+ is going to give us this opportunity to tell even deeper stories about characters you already know and love,” and followed it up with the declaration that “it all, for the first time, will interlink.” By stating that this is the beginning of the movies and TV series connecting, he’s effectively wiped all previous Marvel shows from canon, which WGTC told you he was going to do last month.
That key statement: "it all, for the first time, will interlink," voids the old "It's all connected" promotional blurbs Marvel/Disney pumped out early on.
Is that Netflix only or does it include SHIELD?
It includes SHIELD. Basically Feige - the MCU god - has said (in the article I linked to and elsewhere) basically that nothing Jeph Loeb produced is MCU canon.
You can't "wipe away" all of SHIELD considering the tie-in episodes for Thor 2 and Winter Soldier. I haven't watched the past few seasons though, but there is definitely a point where they just started getting ignored.
Actually, Kevin Feige can, and has from the start. The tie-ins of films with SHIELD were always only one way: from film to TV. Had
anything from the TV series
ever had repercussions in the films, then it would not be so easy. But they didn't. As far as the MCU filmworld was considered, for instance, Coulson was never alive past The Avengers.
They are about to introduce the multiverse, so anything can be wiped away (while also not being wiped away)
True, but with Kevin Feige doing as he's done so far, I doubt he would acknowledge anything that Jeph Loeb produced, regardless of having a multiverse option to explain them. I just don't think he'd spend the film-time (or even Disney+ series time) with them. There's too much he has laid out, and too much MCU story to tell, where any discussion of the "Loeb-verse" would feel like a distracting waste of screen time.
I think the only way they MIGHT show up, is if Disney gives Kevin Feige, a "you must say something about the Jeph Loeb materials, or else," ultimatum. But, given the films he's headed have been such incredible money-makers, I have severe doubts they'd try to force him to do
anything that he didn't want to.
Oh, and after thinking about it more, I agree with your earlier post: re-using a Netflix actor like Charlie Cox in official MCU work would severely muddy the waters about what is and is not canon for those not obsessed enough to visit websites or threads about the MCU.

So I'm OK with leaving it up to the MCU's head of casting (can't recall her name off the top of my head) to recast equally well when Kevin Feige decides to launch the Defenders (and Cloak & Dagger, and The Runaways, etc.) in one of his projects.