#1: Tex Murphy series:
A series of adventure games originally created to be run on DOS and eventually becoming one of the first computer games to use DVD technology. Story focuses around Tex Murphy, a private investigator in post WWIII San Francisco during the late 2030's to the mid 2040's. The Tex Murphy series was always groundbreaking in it's production, interactivity and especially it's humor; but was forced to meet it's end in a rather untimely fashion with the downfall of the adventure game genre.
Examples of Tex humor:
Tex Murphy (upon the player clicking on a certain item in a shop): "Ahh, the Rodent Tracker 5000...Because household pests never build up an immunity to bullets."
Tex relates a story of how he became known as "Tex". He was a young boy, playing cowboy on a mechanical horse when a bolt of lightning caused a power surge and the horse launched him into the ceiling. Afterwards his brothers and sisters noticed the hole he left behind was in the shape of Texas.
#2: Leisure Suit Larry
Scavenger hunt-style animated computer game series following the sexed up exploits of Larry Laffer, a balding, self-described "ladies man" (more like ladies punching bag) with a love of 70's style leisure suits and sufferer of self-delusions. The series did not officially end until The series went down with the rest of the adventure game giants though there was a poorly recieved game featuring Larry's nephew and his exploits at college. The franchise was, however, undeniably dead.
Game Examples from Leisure Suit Larry 7: Love for Sail
Larry attempts to win various shipboard contests to spend a night "Cruising on the captain(yes, the female captain)." In one portion of a cooking contest Larry must procure "beaver cheese" to make quiche and he finds a bunch of beavers in a hamster-style cage stored in one of the ship's holds and proceeds to...ahem...milk them. Thankfully the lights go out but after Larry finishes all the beavers light up cigarettes.
You get extra points in the game if you sit through the animatronic Bill Clinton's entire stand-up comedy act. "Once I was walking along the beach when I found a bottle. I picked it up and rubbed it and a genie came out and said he would grant me a wish. So I thought and thought and finally I said "'I wish for peace in the middle east."' and pulled out a map and the genie said "'I can't grant that wish. These countries have been fighting for thousands and thousands of years. Ask for something else.'" So I thought and thought and finally I said "'Well, then, could you make my wife Hillary the most beautiful, most beloved woman in the world?'" The genie looks at me and says "Give me that damn map."
Well I'm going to TRY not to make this a list exclusively made up of adventure games but I just have to say there were so many great and worthwhile titles and just about all of them got the axe when the 90's ended. The ones above will always be my personal favorites, though. Actually, I don't think I should have all the fun here so why doesn't someone share a favorite game or style of game that they loved and was sad to see die out.